Items where Author is "Häberli, C."

2023

Kasago, F. M. and Häberli, C. and Keiser, J. and Masamba, W.. (2023) Design, synthesis and evaluation of praziquantel analogues and new molecular hybrids as potential antimalarial and anti-schistosomal agents. Molecules, 28 (13). p. 5184.

Muya, K. and Kalonji, M. and Ilunga, N. W. and Maseho, M. and Kitambala, M. and Kalonda, M. and Ndoumba, K. and Byanga, K. and Wright, C. W. and Häberli, C. and Keiser, J. and Simbi, L.. (2023) Evaluation of 43 species of Congolese medicinal plants used traditionally for the treatment of schistosomiasis leading to the isolation of an anti-schistosomal phaeophytin from Pseudolachnostylis maprouneifolia Pax. J Ethnopharmacol, 315. p. 116688.

Biendl, S. and Häberli, C. and Chen, G. and Wang, W. and Zhong, L. and Saunders, J. and Pham, T. and Wang, X. and Wu, J. and Charman, S. A. and Vennerstrom, J. L. and Keiser, J.. (2023) In vitro; and; in vivo; antischistosomal activity profiling and pharmacokinetics of ozonide carboxylic acids. ACS Infect Dis, 9 (3). pp. 643-652.

D'Abbrunzo, I. and Bianco, E. and Gigli, L. and Demitri, N. and Birolo, R. and Chierotti, M. R. and Keiser, J. and Häberli, C. and Voinovich, D. and Hasa, D. and Perissutti, B.. (2023) Praziquantel meets Niclosamide: a dual-drug antiparasitic cocrystal. International journal of pharmaceutics, 644. p. 123315.

2022

Dube, M. and Llanes, D. and Saoud, M. and Rennert, R. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2022) Albatrellus confluens (Alb. & Schwein.) Kotl. & Pouz.: natural fungal compounds and synthetic derivatives with in vitro anthelmintic activities and antiproliferative effects against two human cancer cell lines. Molecules, 27 (9). p. 2950.

Ren, R. and Wang, X. and Leas, D. A. and Häberli, C. and Cal, M. and Dong, Y. and Kaiser, M. and Keiser, J. and Vennerstrom, J. L.. (2022) Antischistosomal tetrahydro-γ-carboline sulfonamides. Bioorganic & medicinal chemistry letters, 59. p. 128546.

Valderas-García, E. and Häberli, C. and Álvarez-Bardón, M. and Escala, N. and Castilla-Gómez de Agüero, V. and de la Vega, J. and Del Olmo, E. and Balaña-Fouce, R. and Keiser, J. and Martínez-Valladares, M.. (2022) Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus. Parasit Vectors, 15. p. 243.

Noce, B. and Di Bello, E. and Zwergel, C. and Fioravanti, R. and Valente, S. and Rotili, D. and Masotti, A. and Ansari, M. S. Z. and Trisciuoglio, D. and Chakrabarti, A. and Romier, C. and Robaa, D. and Sippl, W. and Jung, M. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Chemically diverse S. mansoni HDAC8 inhibitors reduced viability in worm larval and adult stages. ChemMedChem. In press.

Angeli, A. and Ferraroni, M. and Carta, F. and Häberli, C. and Keiser, J. and Costantino, G. and Supuran, C. T.. (2022) Development of Praziquantel sulphonamide derivatives as antischistosomal drugs. J Enzyme Inhib Med Chem, 37 (1). pp. 1479-1494.

Biendl, S. and Häberli, C. and Keiser, J.. (2022) Discovery of novel antischistosomal scaffolds from the open access Pandemic Response Box. Expert Rev Anti Infect Ther, 20 (4). pp. 621-629.

Di Bello, E. and Noce, B. and Fioravanti, R. and Zwergel, C. and Valente, S. and Rotili, D. and Fianco, G. and Trisciuoglio, D. and Mourão, M. M. and Sales, P. and Jr., and Lamotte, S. and Prina, E. and Späth, G. F. and Häberli, C. and Keiser, J. and Mai, A.. (2022) Effects of structurally different HDAC inhibitors against Trypanosoma cruzi, Leishmania, and Schistosoma mansoni. ACS Infect Dis, 8 (7). pp. 1356-1366.

Cantara, A. and Luo, Y. and Dobrovolna, M. and Bohalova, N. and Fojta, M. and Verga, D. and Guittat, L. and Cucchiarini, A. and Savrimoutou, S. and Häberli, C. and Guillon, J. and Keiser, J. and Brazda, V. and Mergny, J. L.. (2022) G-quadruplexes in helminth parasites. Nucleic Acids Res, 50 (5). pp. 2719-2735.

Dube, M. and Raphane, B. and Sethebe, B. and Seputhe, N. and Tiroyakgosi, T. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N. and Andrae-Marobela, K.. (2022) Medicinal plant preparations administered by botswana traditional health practitioners for treatment of worm infections show anthelmintic activities. Plants (Basel), 11 (21). p. 2945.

Hamway, Y. and Zimmermann, K. and Blommers, M. J. J. and Sousa, M. and Häberli, C. and Kulkarni, S. and Skalicky, S. and Hackl, M. and Götte, M. and Keiser, J. and da Costa, C. P. and Spangenberg, T. and Azzaoui, K.. (2022) Modulation of host-parasite interactions with small molecules targeting Schistosoma mansoni microRNAs. ACS Infect Dis, 8. 2028−2034.

Kersting, L. and Kuhn, L. and Anokhin, M. and Schuster, F. and Häberli, C. and Sambyal, S. and Kumar, H. M. S. and Keiser, J. and Alabugin, I. and Tsogoeva, S. B.. (2022) Visible-light-driven metal-free C-H functionalization: access to new bioactive tetrahydroisoquinoline-butenolide hybrids via domino amine oxidation/vinylogous mannich reaction. ChemPhotoChem, 6 (8). e202200109.

2021

Debbert, S. L. and Hintz, M. J. and Bell, C. J. and Earl, K. R. and Forsythe, G. E. and Häberli, C. and Keiser, J.. (2021) Activities of quinoxaline, nitroquinoxaline and [1,2,4]triazolo[4,3-a]quinoxaline analogs of MMV007204 against; Schistosoma mansoni. Antimicrobial agents and chemotherapy, 65 (3). e01370-20.

Dube, M. and Saoud, M. and Rennert, R. and Fotso, G. W. and Andrae-Marobela, K. and Imming, P. and Häberli, C. and Keiser, J. and Arnold, N.. (2021) Anthelmintic activity and cytotoxic effects of compounds isolated from the fruits of Ozoroa insignis del. (Anacardiaceae). Biomolecules, 11 (12). p. 1893.

Keiser, J. and Häberli, C.. (2021) Assessment of FDA-approved drugs against Strongyloides ratti in vitro and in vivo to identify potentially active drugs against strongyloidiasis. Parasit Vectors, 14. p. 615.

Buchter, V. and Hofmann, D. and Häberli, C. and Keiser, J.. (2021) Characterization of moxidectin against; Strongyloides ratti:; in vitro; and; in vivo; activity and pharmacokinetics in the rat model. ACS Infect Dis, 7 (5). pp. 1069-1076.

Keiser, J. and Häberli, C.. (2021) Evaluation of commercially available anthelminthics in laboratory models of human intestinal nematode infections. ACS Infect Dis, 7 (5). pp. 1177-1185.

Probst, A. and Chisanga, K. and Dziwornu, G. A. and Häberli, C. and Keiser, J. and Chibale, K.. (2021) Expanding the activity profile of pyrido[1,2-a]benzimidazoles: synthesis and evaluation of novel n(1)-1-phenylethanamine derivatives against Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1032-1043.

Sirak, B. and Asres, K. and Hailu, A. and Dube, M. and Arnold, N. and Häberli, C. and Keiser, J. and Imming, P.. (2021) In vitro antileishmanial and antischistosomal activities of anemonin isolated from the fresh leaves of Ranunculus multifidus forsk. Molecules, 26 (24). p. 7473.

Probst, A. and Pujol, E. and Häberli, C. and Keiser, J. and Vázquez, S.. (2021) In vitro, in vivo, and ADME evaluation of SF5-containing N,N'-diarylureas as antischistosomal agents. Antimicrobial agents and chemotherapy, 65 (10). e0061521.

Nguyen, W. and Lee, E. F. and Evangelista, M. and Lee, M. and Harris, T. J. and Colman, P. M. and Smith, N. A. and Williams, L. B. and Jarman, K. E. and Lowes, K. N. and Häberli, C. and Keiser, J. and Smith, B. J. and Fairlie, W. D. and Sleebs, B. E.. (2021) Optimization of benzothiazole and thiazole hydrazones as inhibitors of schistosome bcl-2a. ACS Infect Dis, 7 (5). pp. 1143-1163.

Partridge, F. A. and Bataille, C. J. R. and Forman, R. and Marriott, A. E. and Forde-Thomas, J. and Häberli, C. and Dinsdale, R. L. and O'Sullivan, J. D. B. and Willis, N. J. and Wynne, G. M. and Whiteland, H. and Archer, J. and Steven, A. and Keiser, J. and Turner, J. D. and Hoffmann, K. F. and Taylor, M. J. and Else, K. J. and Russell, A. J. and Sattelle, D. B.. (2021) Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites: Trichuris muris, Brugia malayi, Heligmosomoides polygyrus, and Schistosoma mansoni. ACS Infect Dis, 7 (5). pp. 1260-1274.